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Categories Ketamine

Got PTSD? Kalypso Ketamine® Can Help Remove the Trauma

Approximately 8 percent of American adults (1 in 13) will develop post-traumatic stress disorder (PTSD) during their lifetime, according to recent research. Those odds have kept medical professionals busy for decades trying to find an effective treatment.

One such treatment that has been gaining momentum in the last few years is ketamine. While previously known primarily as an anesthetic for many decades, the last few years have seen ketamine emerge as a popular pain management solution for several types of chronic physical pain and psychological disorders—including PTSD.

At Kalypso Wellness Centers, ketamine is administered intravenously, with one infusion lasting about 60 minutes. Because ketamine inhibits NMDA receptors in the body that are responsible for central sensitization, ketamine infusions work in a completely different way from any other medication. Many antidepressant medications serve to “block” certain pathways but do not eliminate the source of the problem. Ketamine works by “re-setting” neural pathways and triggering a rapid growth of neural connections, thus removing the traumatic experience from memory.

“It blocks a pain receptor that none of the ‘morphine type’ of drugs block,” Kalypso Wellness Centers CEO Dr. Cannon Clifton said. “This is a central receptor, so key to blocking pain at its source. And since all the other pain medicines block different receptors, the patients are not sensitized to ketamine and reply very quickly.”

One study of ketamine’s effectiveness in treating patients with PTSD indicated that “Several patients did not receive a second infusion per protocol because of sustained reduction in PTSD symptom levels.” Last year, John Krystal, M.D., Chair of the Yale University Department of Psychiatry, said in a statement, “Ketamine seems to rapidly and robustly improve (PTSD) symptoms, even for individuals who have tried a myriad of other medications and treatment approaches with little to no benefit.”

Kalypso Wellness Centers has experienced success of its own using its patent-pending Kalypso Ketamine® infusions to treat patients suffering from PTSD. We know ketamine has been successful treating PTSD because the patients themselves have told us. According to H.T. from Boerne, Texas, “I had horrible PTSD and anxiety until my treatments with Kalypso. Now my PTSD and anxiety are cured! I haven’t had any problems with PTSD or anxiety for months!”

And ketamine works quickly. Patients who receive the recommended treatment of 4 to 6 infusions over a 2- to 3-week period receive 90 to 95 percent relief. And sometimes it even works faster. M.H. from San Antonio declared, “I had nightmares from Vietnam every night for 40 years, after one infusion they were gone!”

The effectiveness of Kalypso Ketamine® infusions in treating PTSD and other debilitating disorders has led to rapid expansion for Kalypso Wellness Centers. Earlier this year, we expanded into the Northeastern U.S. when we entered into a partnership with renowned pain management specialist Dr. Edward S. Rubin M.D. in Garden City, New York. Kalypso Wellness Centers now features six locations in the U.S.: Corpus Christi, Houston, and San Antonio in Texas; Garden City, New York; Meridian, Mississippi; and Wilmington, North Carolina. In fact, we just recently administered our 4,000th Kalypso Ketamine infusion®. Contact us if you are suffering, and we will help you reset your life the way we have already helped thousands in just over two years of existence.

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Categories Press Release

Kalypso Wellness Centers Partner with South Texas Mental Health Associates


Picture fo Dr Talley with yellow background Dr Lusins with blue background

Kalypso Wellness Centers partner with South Texas Mental Health Associates to offer Kalypso Ketamine® infusion treatments in Corpus Christi

CORPUS CHRISTI, Texas (December 13, 2018)— Kalypso Wellness Centers, one of the most successful, and rapidly expanding, ketamine clinics in the country, has partnered with South Texas Mental Health Associates to bring Kalypso’s revolutionary ketamine treatments to patients suffering from depression, anxiety, and other psychiatric disorders.

South Texas Mental Health Associates, located in Corpus Christi, recently became a managed clinic for Kalypso Wellness Centers to provide treatment in the form of Kalypso Ketamine® infusions that was previously available only by driving two to four hours to San Antonio or Houston. The reputation of the patent-pending Kalypso Ketamine® infusions as an effective method for treating more than 30 disease states has been growing rapidly since Kalypso Wellness Centers was launched in 2016.  Earlier in 2018, Kalypso surpassed two major milestones: first, its 3,000th ketamine infusion in May, and then a few months later, its 4,000th.

“We wanted a partner that had proven success with their products and business model, thus with over 4,000 infusions, Kalypso was the logical choice,” said Dr. John Lusins, a psychiatrist who started South Texas Mental Health Associates. “Kalypso has differentiated themselves from other providers with not only their track record of success but most importantly excellent patient feedback.”

Ketamine is an anesthetic, but in recent years has gained popularity in treating patients with chronic, debilitating pain, dependency on narcotics, depression, PTSD, and a host of other ailments. Ketamine works by essentially “re-setting” neural pathways and triggering a rapid growth of neural connections, thus stopping the problem at its source. Studies on the benefits of ketamine have been performed at Yale University, the National Institute of Health, Harvard University, Johns Hopkins, and others.

“We started in Texas, and we have successful locations in Houston and San Antonio, so the expansion into Corpus Christi is the natural next step for us,” said Dr. Cannon Clifton, CEO of Kalypso Wellness Centers. “We are honored to add South Texas Mental Health Associates to our list of managed clinics, and we are proud to have the talents and experience of Dr. John Lusins and Dr. Megan Talley on our side as we continue to help suffering patients reset their lives with our cutting-edge ketamine infusions. We plan to expand the practice further. Our goal is to make ketamine the mainstream treatment instead of the alternative treatment.”

The addition of South Texas Mental Health Associates to the Kalypso family continues the practice’s rapid expansion. Now, just over two years since its formation, Kalypso features locations in North Houston and San Antonio as well as managed clinics in Corpus Christi, TX, Garden City, New York; Meridian, Mississippi; and Wilmington, North Carolina. The success of Kalypso Ketamine infusions in managing chronic pain, depression, PTSD, migraines, and other disease states has been largely responsible for the way the practice has expanded in such a short time. Kalypso’s unique formulations have resulted in 90-96% efficacy with a side effect rate of only 5%.


About Kalypso Wellness Centers

Kalypso Wellness Centers was formed in 2016 by two board-certified anesthesiologists Dr. Cannon Clifton, CEO and Dr. Bryan Clifton, CMO; and two board-certified pain management physicians, Dr. Mark Moran, Chief Science Officer and Dr. Scott Worrich, Chief Clinical Officer who were tired of seeing patients needlessly suffering and chronically debilitated on prescription narcotics. After countless months of research, they found a promising new solution with the use of ketamine infusions that could be offered to patients. As treatments continued, they created the RESET Ketamine Therapy®, which includes five distinct proprietary ketamine formulations: KalypsoCalm®, KalypsoCan®, KalyMax®, KalyPro® and KalypsoZen®.  Upon further investigation, they discovered that when tailored to each patient’s unique disease state, these infusions can provide a substantial improvement in quality of life for patients with anxiety, major depressive disorder, PTSD, bipolar disorder, fibromyalgia, neuropathic pain, inflammatory pain, chronic pain, and migraines/chronic headaches. Kalypso Ketamine is offered in 6 locations—three in Texas and one each in New York, Mississippi, and North Carolina.

For more information, visit

About South Texas Mental Health Associates

South Texas Mental Health Associates is an adult psychiatric outpatient clinic based in Corpus Christi, Texas. The team at South Texas Mental Health Associates provides comprehensive patient-oriented care to address mental health issues including depression, anxiety, bipolar disorder, mood disorders, ADHD, schizophrenia, and more. The team of psychiatrists and nurse practitioners focuses on evidence-based treatments, including medication and therapies customized to address the specific concerns and needs of each individual patient. The environment at South Texas Medical Associates is calm and inviting, so patients and their families can relax and focus on their care.

For more information, visit

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Categories Press Release

Kalypso Wellness Centers Moves to Secure Patent for Ketamine Treatments

SAN ANTONIO, Aug. 21, 2018— Kalypso Wellness Centers, a leader in advanced ketamine infusion treatments for PTSD, depression, chronic pain, and many other conditions, announced today that it has filed a patent for its groundbreaking Kalypso Ketamine™ infusion process. Ketamine treatments are becoming increasingly popular around the country as an alternative method for treating debilitating disorders and conditions that have proven difficult to treat using traditional medicine.

“We decided that now is the right time to patent our process because we feel that our formulations and treatment methods provide patients with a better experience with less side effects,” said Dr. Bryan Clifton, Kalypso’s Chief Medical Officer. “Our infusions take an hour and most patients see benefits after their first treatment. Kalypso RESET formulations have demonstrated an 85% to 95% clinical efficacy rate and adverse side effect rate of less than 5%.”

Once approved, the patent will be in effect for 20 years and it will apply to all five of Kalypso’s proprietary ketamine formulations and any future ketamine formulations developed by Kalypso. The patent also covers all routes of ketamine administration for currently recognized clinical applications and any potential future uses.

“We feel confident Kalypso Ketamine is beyond the state of the art and we want to ensure that there is a standard that people adhere to as it relates to administrating ketamine treatments and how they should properly use our formulations,” Dr. Clifton said.

Since Kalypso will be the first to apply for a patent for these formulations and methodology, the company will be spending more time in Washington, D.C., advocating for patients’ safety and helping establish the standard of care for ketamine treatments.

Currently, Kalypso offers its revolutionary Kalypso Ketamine™ treatments at its five clinics—three in Texas, one in North Carolina, and one in New York. To date, Kalypso has administered approximately 3,500 ketamine infusions.

Business Insider

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Categories Depression, Ketamine

Depression and Ketamine

For sufferers of depression and suicidal ideation, Kalypso Ketamine™ may save lives

Ketamine was first used as an anesthetic some 50 years ago, and in smaller doses it works to ease physical pain. When taken in larger doses, ketamine has been known to cause the user to experience hallucinations, thus making it a popular recreational drug over the decades.

In the last 20 years, another use of ketamine has been discovered that may literally save lives—combatting depression and suicidal ideation.

Many studies have been conducted since then to determine just how effective ketamine is as an antidepressant, and scientists have found that when it works, it works quickly. Antidepressants generally take weeks before users feel the effects; when ketamine is taken, either intravenously or with a nasal spray, it often takes effect in a matter of hours. Read More Depression and Ketamine

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Categories Press Release

Kalypso Wellness Centers Groundbreaking Approach to Pain Treatment Leads to Company Reaching 3K Milestone

SAN ANTONIO, May 15, 2018: Kalypso Wellness Centers, a leader in advanced ketamine infusion treatment for chronic pain, PTSD, migraine headaches, depression, fibromyalgia and many other conditions, has reached a medical milestone – it’s performed 3,000 Kalypso Ketamine™ infusion treatments in less than two years.

“We have achieved phenomenal growth in such a short amount of time because ketamine has become an extremely popular way to treat various disorders and illnesses that are extremely difficult to treat using traditional medicine, such as PTSD, neuropathic pain, migraine headaches, anxiety, and inflammatory pain,” said Dr. Cannon Clifton, Kalypso Wellness Centers CEO and founder.

Dr. Clifton believes that Kalypso Wellness Centers reached its 3,000 infusion treatment milestone because of the effectiveness of their treatment methods on patients and the lack of side effects their treatment method causes compared to generic ketamine.

Kalypso Wellness Centers utilize five distinct proprietary ketamine formulations and tailor the infusions to each patient’s unique disease state. As a result, hundreds who had previously suffered for many years have been able to substantially improve their quality of life. Ketamine, which has traditionally been known as an anesthetic or a recreational drug, is fast gaining a reputation as an alternative method for pain management and depression.

Because of the success Kalypso Wellness Centers have had with their proprietary ketamine infusions — a 90% clinical efficacy rate and a 5% adverse side affect rate — Kalypso’s founders have been able to expand their practice to three clinics across Texas (San Antonio, Corpus Christi, North Houston) and one clinic in North Carolina. They expect to open additional clinics soon.

Kalypso was founded in 2016 by two board certified anesthesiologists and two board certified pain management doctors, now features four clinics. The company expects to launch new therapies in the new future. Dr. Scott Worrich, Kalypso Wellness Centers Chief Clinical Officer, continues to investigate innovative formulations that will benefit patients.

“We spend a significant amount of time researching various medicines and formulations to optimize our treatments for specific conditions. Our customized treatments offer significant value to patients as evidenced by the 31 different disease states we have treated at our clinics. Our slogan is ‘RESET…for life’ because our Kalypso Ketamine™ infusions help people ‘reset’ their lives,” Dr. Clifton said. “We have helped hundreds of people reset their lives, and we are going to help thousands more. I believe that in the not-too-distant future, ketamine will be the rule and not the exception.”

Dallas Business Journal